Vor Biopharma Inc.
We make healthy cells invisible to targeted therapiesTargeted therapies work by attacking cells that express particular proteins on their surface. Unfortunately, both diseased and healthy cells often express the same proteins, resulting in collateral damage to healthy cells.At Vor, we engineer hematopoietic stem cells (HSCs) to lack a biologically redundant target protein, then transplant these cells into the patient.These eHSCs give rise to generations of new healthy blood cells that are effectively invisible to targeted therapies. Diseased cells displaying the target protein and are then vulnerable to attack. This process potentially broadens the therapeutic window and improves the utility of complementary targeted therapies.Please visit our website at https://www.vorbio.com/ for more information.As an equal opportunity employer, we at Vor Biopharma know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.In an effort to protect our coworkers and communities from COVID-19, Vor Biopharma Inc. requires all employees to be fully vaccinated against COVID-19 unless they receive an approved reasonable accommodation for medical or religious reasons.What we value in our fellow VoraciansPassion: Enthusiastically driving our science toward innovative medicinesFellowship: Fostering genuine bonds of collaboration and mentorshipHumility: Acting selflessly by putting the collective mission firstWho we are looking for:Vor Biopharma is seeking a Manufacturing Specialist who will be an integral part of building an in-house manufacturing site and associated processes. The candidate will be responsible for executing the manufacturing of Vor’s clinical therapies and maintaining compliance to cGMPs in the manufacturing areas. Additionally, the ideal candidate will support tech transfer activities by working with the MSAT and PD groups.Key areas of responsibilities:* Support/perform cleanroom operations, including reviewing and tracking of equipment records for PM/calibration and cleanroom maintenance and cleaning* Work with the Process Development and MSAT groups to support the development of manufacturing processes to the internal manufacturing site* Strict adherence to current good manufacturing practices, standard operating procedures, and manufacturing documentation* Establish and follow written procedures for clear and accurate documentation of equipment operation and process instructions and of process dataQualifications:* BS or MS in Biology, Biochemistry, Engineering, or related field* 1 – 5 years of experience in cGMP manufacturing with hands-on experience in cell therapy production and aseptic manufacturing techniques#LI-DNI