Lead Research Specialist, Endocrinology

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Description

The laboratory of Dr.

Dan Perrien has an immediate opening for a Lead Research Specialist.

Dr.

Perrien’s lab, in the Division of Endocrinology, Metabolism, and Lipids, uses genetically modified mice, cell culture, and molecular techniques to understand regulators of a rare musculoskeletal disease, including BMP signaling and immune interactions with bone cells.

The candidate must have demonstrated experience with animal handling, in vivo imaging, PCR, RT-qPCR, flow cytometry/FACS, and cell culture.

Position requires rodent handling.

Experience in the field of bone biology or immunology is not necessary but would be advantageous.

JOB DESCRIPTION:

• Under minimal supervision, performs a variety of specialized and complex research and laboratory tests and procedures.
• Uses independent judgment in applying or adapting scientific techniques.
• May assist in protocol design.
• Investigates and proposes alternative experimental procedures for consideration by a principal investigator.
• Assists in planning and scheduling research procedures.
• Analyzes and interprets results of studies.
• Demonstrates and trains others in the proper use/operation of laboratory techniques and equipment.
• Calibrates, troubleshoots and performs routine repair and maintenance of equipment.
• Reviews literature for related research developments and techniques and compiles findings.
• Monitors laboratory processes to maintain quality assurance standards.
• Records results of studies, compiles and analyzes data and prepares charts and graphs.
• Monitors the handling, storage and disposal of hazardous substances.
• Performs related responsibilities as required.
• Employees in this classification may be required to work with, take specific precautions against and/or be immunized against potentially hazardous agents.

Job Duties:

• Design and write experimental protocols under the direction of the PI and accurately document all laboratory activities
• Report data to the PI in written, graphical, and oral communications.
• Conduct studies in mice including breeding, genotyping, injections, gavage, minor surgery, and necropsy
• Perform x-ray imaging and other imaging of live rodents
• Ex vivo analyses of tissues including histology, immunohistochemistry, and protein and mRNA extractions and analyses.
• Conduct tissue culture studies using primary and transformed cells
• Maintain laboratory supplies and equipment
• Maintain chemical and biological inventory and safety documentation
• Train or assist in training of new students and staff
• Most duties will be performed on a semi
  – to fully-independent basis

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in a scientific field and two years of research experience, or equivalent combination of experience, education, and training.

PREFERRED QUALIFICATIONS:

• Minimum Education: BA/BS in Biological Sciences or closely related field
• 4 years of biomedical research experience
• Willingness to work with rodents in a laboratory setting
• At least 3 years of experience handling small laboratory animals
• Some experience with tissue culture
• Experience with PCR and other standard laboratory techniques
• Excellent written and verbal communication skills
• Demonstrated ability to work with others in a positive and productive manner
• Willingness to perform some weekend and afterhours

Any combination of the following skills/experience would be advantageous:

• Management of genetically modified mouse colonies, including genotyping and husbandry
• Flow cytometry
• qPCR/RT-qPCR
• Histological staining and analysis using brightfield and/or epifluorescence
• In vivo imaging of live rodents using any modality
• Small animal necropsy and surgery
• Western blot
• IHC and/or ISH
• Site directed mutagenesis and plasmid preps
• Plate-based assays such as ELISAs and luciferase assays

NOTE: Position tasks are required to be performed in-person at an Emory University location; working remote is not an option.

Emory reserves the right to change this status with notice to employee.

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Please note that one week advance notice is preferred.