Clover Therapeutics Company
Clover Therapeutics – Scientist/Senior Scientist, Stem Cell Biology Clover Therapeutics has built a large, re-contactable, and longitudinal patient community dedicated to developing precision medicine approaches for diseases of aging.
Our research platform combines genetics with deeply-phenotyped longitudinal patient populations to uncover the genetic basis of disease progression.
We pursue drug discovery programs with genetically-supported targets and develop companion diagnostics that match drug mechanisms with patient genetic risk profiles.We are seeking a highly talented Scientist/Senior Scientist to lead our human iPSC platform.
This role will develop iPSC-based in vitro models for target validation, biomarker discovery and diagnostics research.
Clover Therapeutics provides an exceptional research opportunity with a unique patient cohort with rich clinical data, machine learning technologies and computational resources to support our research activities.
This position offers an opportunity to join a dynamic growing team and contribute to the discovery and development of novel therapeutics.
Ideal candidates will have expertise in human stem cell biology, iPSC differentiation protocols, cell-based assay development and project leadership.Responsibilities:Develop and execute protocols to differentiate human iPSC lines into cell types and organoids to support drug discovery research, with initial focus on ophthalmology therapeuticsDevelop and execute strategies for in vitro target modulationContribute to the evaluation of disease pathways and drug targetsLead target validation and early drug discovery researchManage and mentor research associatesEstablish and manage research activities with external collaborators and CROsRegularly present data and strategy to internal and external audiences of diverse scientific backgroundsKey qualifications:Ph.D.
in a relevant biological disciplineAt least 2 years postdoctoral research experienceAt least 3 years hands-on experience in differentiating human iPSC lines into relevant cell types and organoidsExperience in genetic manipulation of human cells including viral transduction, CRISPR based gene editing, siRNA knockdown, etcSuccessful leadership of independent research programsA track record of scientific excellence as demonstrated by publications or patentsSupervisory experienceExcellent communication and collaborative working skills