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Director of Enterprise Architecture – R&D

Vertex Pharmaceuticals

This is a Full-time position in Boston, MA posted November 7, 2021.

Director of Enterprise Architecture
– R&D

Vertex is seeking a unique individual who can play a role at the intersection of science, data and technology to enable life changing impacts to people’s lives.

We seek a leader who can apply Enterprise Architecture practices to empower Vertex to create transformative medicines in bold new ways.

This includes collaborating with business and Data, Technology and Engineering (DTE) leaders to transform organizations, roles, processes and technologies.

It involves deriving targeted strategic business outcomes, defining future state blueprints to achieve those outcomes, and defining strategic roadmaps to realize the future blueprint and outcomes.

This position leads Enterprise Architecture for the Research and Pre-Clinical Sciences (RPPS) and Vertex Cell and Gene Therapy (VCGT) business functions .

The successful candidate must have deep experience applying Enterprise Architecture practices to achieve significant business results in this function. The candidate will interact directly with senior business leaders, scientists and other key Vertex stakeholders to define strategic technology plans and oversee solution architecture. 

While the focus will be on RPPS/VCGT , the successful candidate will also ensure that architectural plans and solutions in this area aligns with an overall enterprise business and technology strategy.

Reporting to the Sr.

Director, Head of Enterprise Architecture the position is part of a new, small and growing Enterprise Architecture Team. Because this is a new, small and growing team, improving Enterprise Architecture capabilities will be a key responsibility of this role.

Accountability & responsibility:

  • Work with RPPS/VCGT stakeholders to drive business and technology strategy
  • Collaboratively influence business stakeholders on strategic outcomes and the best architecture to achieve them.
  • Create/define enterprise architecture roadmaps and ensure business and DTE alignment.

    These roadmaps include business, application, information, integration and infrastructure views.

  • Help to define/manage/drive all things DTE architecture – tools, frameworks, standards, processes, implementation and governance.
  • Work with business and IT stakeholders on strategic business and DTE initiatives.
  • Develop and maintain a current/future state architecture that achieves business goals in a customer-focused manner.
  • Lead diverse, multidisciplinary teams of systems, cloud, solution and application architects
  • Lead architecture reviews of technology initiatives
  • Lead teams through application rationalization activities.
  • Develop in-depth knowledge of strategic, tactical and operational business requirements
  • Ability to conceptualize and develop alternative solution approaches, articulating the benefits and tradeoffs of each solution
  • Investigate and understand industry trends and emerging technologies, and plan for adoption where appropriate
  • Proven track record in consistent and timely delivery of high-quality products and services within budget
  • Demonstrate leadership and influence skills across organizational levels and functions
  • Proven track record leading highly effective teams in strategic planning, enterprise and systems architectures and design/development of strategic business solutions

Skills & Experience:

  • Deep experience in supporting a Biotech research and development capability from an Enterprise Architecture perspective.
  • Clear understanding of Biotech research process and key concerns that researchers and pre-clinical scientists stakeholders face.
  • Strong knowledge of current digital trends, disruptive forces, and modern business and technology concepts
  • Expertise in cloud architectures and concepts
  • 10+ years senior leadership experience, in a large, global pharmaceutical organization architecting and designing technology solutions in an innovative and realistic manner that focuses on delivery
  • Ability to balance high-level identification of innovation opportunities with oversight of business and technology capability development processes
  • Demonstrated technical and business aptitude that allows you to understand, translate, and guide discussions and decisions at a strategic enterprise level as well as at a detailed execution level
  • Demonstrated ability for development of global strategic plans including analysis, strategic priorities, capabilities and multi-year plans with supporting operating plans.
  • Ability to translate complex business strategies and needs into strategic priorities that leverage industry trends and emerging technologies while integrating existing architectures, platforms and data.
  • Ability to consolidate complex existing environmental descriptions into an existing Architecture for a current state architecture and the development of an ongoing future state Architecture.
  • Proven track record re-platforming highly-complex and large scale legacy systems for global customers.
  • Experience in leading development of Micro services and containerized application (Docker images or Kubernetes) with expertise in distributed cache and load balancing.
  • Experience with SOA, design patterns, web services technologies, APIs, Applications, Application Ecosystem, and Micro API’s.
  • Experience in architecting solutions with information security built-in and that account for and incorporate relevant security governance in the ongoing lifecycle of design and engineering
  • Must have relevant cloud experience and assist in the transition to a “cloud-first” and cloud-platform direction for the company products
  • Must possess a unique blend of business and technical savvy; a big-picture vision, and the drive to make that vision a reality.

Education:

  • BS in Computer Science, Software Engineering or other related technology degree
  • Masters in Business or Masters in Technology preferred

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law.

Vertex is an E-Verify Employer in the United States.

Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com.

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases.

The company has three approved medicines that treat the underlying cause of cystic fibrosis (CF) – a rare, life-threatening genetic disease — and has several ongoing clinical and research programs in CF.

Beyond CF, Vertex has a robust pipeline of investigational medicines in other serious diseases where it has deep insight into causal human biology, such as sickle cell disease, beta thalassemia, pain, alpha-1 antitrypsin deficiency, Duchenne muscular dystrophy and APOL1-mediated kidney disease.

Founded in 1989 in Cambridge, Mass., Vertex’s global headquarters is now located in Boston’s Innovation District and its international headquarters is in London, UK.

Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia and Latin America.

Vertex is consistently recognized as one of the industry’s top places to work, including nine consecutive years on Science magazine’s Top Employers list and top five on the 2019 Best Employers for Diversity list by Forbes.

For company updates and to learn more about Vertex’s history of innovation visit or follow us on Facebook , Twitter , LinkedIn , YouTube and Instagram .

The diversity and authenticity of our people is part of what makes Vertex unique, and we recognize that each employee brings diverse perspectives and strengths.

By embracing those strengths and celebrating differences, we are fostering an inclusive culture where each of us can bring our authentic selves to work, inspire innovation together, and change people’s lives.

Our vision is clear: to be the place where an authentic, diverse mix of talent want to come, to stay, and do their best work.

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